Treatment results and prognostic factors in inoperable carcinoma of the cervix treated with external plus high dose brachytherapy


Garipagaoglu M., Yalvac S., Kose M., Tulunay G., Kayikcioglu F., Cakmak A., ...Daha Fazla

CANCER LETTERS, cilt.136, ss.17-26, 1999 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 136 Konu: 1
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0304-3835(98)00293-6
  • Dergi Adı: CANCER LETTERS
  • Sayfa Sayıları: ss.17-26

Özet

Patients with inoperable carcinoma of the cervix treated with external plus high dose rate brachytherapy (HDRB), between 1988 and 1995 were evaluated retrospectively. According to stage, 5 year survival rates were 67.3% in stage IIb and 52.6% in stage III (P = 0001) and disease free survival (DFS) rates were 54.0% in stage IIb and 43.9% in stage III (P = 0.01), The following parameters were studied: age; stage; external beam dose; brachytherapy dose; total dose to point A; tumor mass; tumor response rate; bilateral or unilateral invasion of parametria in stage IIb; and bilateral or unilateral invasion of pelvic wall in stage mb; and the existence of hydronephrosis. The only significant parameter of 5 year survival and local control was tumor mass (P = 0.003). (C) 1999 Published by Elsevier Science Ireland Ltd, All rights reserved.