Frequency of germline BRCA1/2 mutations and association with clinicopathological characteristics in Turkish women with epithelial ovarian cancer

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Sunar V., Korkmaz V., Topcu V., Cavdarli B., ARIK Z., Ozdal B., ...More

ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, vol.18, no.1, pp.84-92, 2022 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 18 Issue: 1
• Publication Date: 2022
• Doi Number: 10.1111/ajco.13520
• Journal Name: ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
• Page Numbers: pp.84-92
• Keywords: BRCA1, BRCA2, family history, germline mutation, ovarian cancer, ASHKENAZI JEWISH WOMEN, NATIONWIDE MULTICENTER, FOUNDER MUTATIONS, JAPANESE PATIENTS, FALLOPIAN-TUBE, BREAST-CANCER, GENES, VARIANTS, RISK, PREVALENCE
• Hacettepe University Affiliated: Yes

Abstract

Aim This study aims to determine the frequency of germline BRCA 1/2 mutations in Turkish women with epithelial ovarian cancer (EOC) and evaluate its relationship with clinicopathological characteristics.