Rice bodies in children with rheumatic disorders: A case series and systematic literature review

ŞENER S., Tanali G., ERGEN F. B., KASAP CÜCEOĞLU M., BALIK Z., BAYINDIR Y., ...More

MODERN RHEUMATOLOGY, vol.33, pp.811-816, 2023 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 33
  • Publication Date: 2023
  • Doi Number: 10.1093/mr/roac075
  • Journal Name: MODERN RHEUMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Page Numbers: pp.811-816
  • Keywords: Arthralgia, children, juvenile idiopathic arthritis, rice body, JUVENILE IDIOPATHIC ARTHRITIS, SUBACROMIAL-SUBDELTOID BURSA, BODY FORMATION, TUBERCULOSIS INFECTION, BURSITIS, DISEASE, TENOSYNOVITIS, PATIENT, LIGHT, KNEE
  • Hacettepe University Affiliated: Yes

Abstract

Objectives Rice body (RB) formation is an uncommon inflammatory process seen in systemic disorders. In this study, we aimed to assess characteristic features of RBs in pediatric patients. Method We retrospectively evaluated pediatric patients who underwent joint/extremity magnetic resonance imaging. A systematic literature review was conducted for articles including children with RBs. Results We found 24 patients (median age 6.1 years; F/M = 2.4) with RBs [23 with juvenile idiopathic arthritis (JIA) and one with arthralgia]. The most prevalent location for RBs was the knee joint (75%). RBs were most frequently seen as diffuse multiple millimetric structures. In three out of five patients with follow-up magnetic resonance imaging, resolution or regression of RBs was observed without surgical intervention. Our literature search identified 13 pediatric patients with RBs. Most (84.6%) had JIA, and the knee joint (71.4%) was the most commonly affected joint. Surgery was preferred in our 3 patients (12.5%) and 10 literature patients (83.3%) in the treatment. Conclusion Our results showed that RBs were most commonly detected in the knee joint, and most cases were secondary to JIA. Although surgery is used as a treatment option, we observed that RBs can occasionally disappear during follow-up without surgical intervention.