We introduce the MATHematics Digital Escape Rooms—MATH-DIGGER platform, which is an Erasmus + project, designed to empower students in their learning process. MATH-DIGGER aims to provide a stimulating innovative learning and teaching practice, using escape rooms. Students solve several challenges (puzzles, quizzes, etc.) in a limited amount of time, to escape a virtual room. Furthermore, MATH-DIGGER seeks to support students’ digital capabilities, and other essential skills, including entrepreneurship, communication, teamwork, negotiation and persuasion, problem solving, leadership, organization, perseverance and motivation, ability to work under pressure, and confidence, which are core skills for their future professional success. There will be an emphasis on females’ active participation in STEM and STEAM areas. Considerations are made to Math curricula development, including these educational games, and new assessment tools. Several Higher Education Institutions (HEIs), and one company are involved in this project. MATH-DIGGER is meant to set a benchmark for the development and implementation of escape rooms in mathematics subjects, in HEIs.