Umbilical cord mesenchymal stromal cells engraft and transdifferentiate into cardiomyocyte-like cells following acute myocardial ischemia


Yigman Z., Ozdemir E. D. , Turan N. N. , ULUS A. T. , CAN A.

ACTA HISTOCHEMICA, cilt.122, sa.6, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 122 Konu: 6
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.acthis.2020.151578
  • Dergi Adı: ACTA HISTOCHEMICA

Özet

Objective: Human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs) gained importance in acute/chronic ischemic cardiomyopathy because of their outstanding regenerative potential in various pathologic conditions. The present study was designed to determine to what extent hUC-MSCs contribute to myocardial regeneration in acute experimental myocardial infarction (MI) in rats.