Umbilical cord mesenchymal stromal cells engraft and transdifferentiate into cardiomyocyte-like cells following acute myocardial ischemia

Yigman Z., Ozdemir E. D., Turan N. N., ULUS A. T., CAN A.

ACTA HISTOCHEMICA, vol.122, no.6, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 122 Issue: 6
  • Publication Date: 2020
  • Doi Number: 10.1016/j.acthis.2020.151578
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Communication Abstracts, EMBASE, MEDLINE, Metadex, Civil Engineering Abstracts
  • Hacettepe University Affiliated: No


Objective: Human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs) gained importance in acute/chronic ischemic cardiomyopathy because of their outstanding regenerative potential in various pathologic conditions. The present study was designed to determine to what extent hUC-MSCs contribute to myocardial regeneration in acute experimental myocardial infarction (MI) in rats.