Regulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases by basic fibroblast growth factor and dexamethasone in periodontal ligament cells


Hakki S. S. , Hakki E. E. , Nohutcu R. M.

JOURNAL OF PERIODONTAL RESEARCH, cilt.44, sa.6, ss.794-802, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Konu: 6
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1111/j.1600-0765.2008.01192.x
  • Dergi Adı: JOURNAL OF PERIODONTAL RESEARCH
  • Sayfa Sayıları: ss.794-802

Özet

Background and Objectives: In this study, we investigated the effect of basic fibroblast growth factor (bFGF) and dexamethasone (Dex) on mRNA expressions of collagen (COL) type I, III and X, matrix metalloproteinases (MMP)-1, -2, -3 and -9 and tissue inhibitors of metalloproteinases (TIMP)-1 and -2, and also on mineralization and morphology of periodontal ligament (PDL) cells.