Does tamoxifen citrate prevent pulmonary fibrosis due to silica inhalation?


Karaca T., Yoldas O., Bilgin B. C. , Yilmaz O. H. , Karaca N., Simsek G. G. , ...Daha Fazla

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.116, sa.7, ss.440-445, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 116 Konu: 7
  • Basım Tarihi: 2015
  • Doi Numarası: 10.4149/bll_2015_083
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Sayfa Sayıları: ss.440-445

Özet

BACKGROUND: As shown in several studies, besides being used in breast cancer, tamoxifen is also known for its antifibrotic effects via reducing the serum TGF-beta levels. We investigated the possible preventive effect of tamoxifen in rats exposed to silica particles depending on the antifibrotic effect.