A constrained, force-directed layout algorithm for biological pathways
GRAPH DRAWING, cilt.2912, ss.314-319, 2004 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 2912
- Basım Tarihi: 2004
- Dergi Adı: GRAPH DRAWING
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.314-319
- Hacettepe Üniversitesi Adresli: Hayır
Özet
We present a new elegant algorithm for layout of biological signaling pathways. It uses a force-directed layout scheme, taking into account directional and regional constraints enforced by different molecular interaction types and subcellular locations in a cell. The algorithm has been successfully implemented as part of a pathway integration and analysis toolkit named PATIKA, and results with respect to computational complexity and quality of the layout have been found satisfactory.