Retroperitoneal Abscess in Severe Combined Immunodeficiency Probably Due to BCG Vaccine

Gur Cetinkaya P., Cagdas D. N., Ozcelik U., Tezcan I.

ASTIM ALLERJI IMMUNOLOJI, vol.18, no.2, pp.98-101, 2020 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.21911/aai.491
  • Journal Name: ASTIM ALLERJI IMMUNOLOJI
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.98-101
  • Keywords: Hematopoietic stem cell transplantation, mycobacterium tuberculosis, primary immunodeficiency, retroperitoneal abscess, severe combined immunodeficiency, CHEST-WALL ABSCESS, TRANSPLANTATION, COMPLICATIONS, INFECTION
  • Hacettepe University Affiliated: Yes

Abstract

Severe combined immunodeficiency (SCID) is characterized by the impairment of T cells with or without B and Natural Killer (NK) cells, leading to recurrent bacterial and viral infections. Although hematopoietic stem cell transplantation (HSCT) is the curative treatment of SCID, many complications and especially infections can develop afterwards. Herein, we report a seven-month-old girl who was diagnosed with SCID and underwent HSCT from HLA-full-matched related donor. However, the patient was complicated with retroperitoneal abscess and chest wall granuloma following HSCI, probably due to the Bacillus Calmette Guerin (BCG) vaccine. Me symptoms of the patient were controlled with anti-tuberculosis therapy and intravenous antibiotics.