A comparison of procaine penicillin with sulbactam-ampicillin in the treatment of peritonsillar abscesses

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Yilmaz T., Ünal Ö. F., Figen G., Akyol M. U., Ayas K.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, cilt.255, sa.3, ss.163-165, 1998 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 255 Sayı: 3
  • Basım Tarihi: 1998
  • Doi Numarası: 10.1007/s004050050035
  • Dergi Adı: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.163-165
  • Hacettepe Üniversitesi Adresli: Evet

Özet

The clinical efficacy of procaine penicillin and sulbactam-ampicillin was compared in patients with peritonsillar abscesses after peroral abscess drainage. Forty-two patients were randomly assigned to receive either procaine penicillin or sulbactam-ampicillin intramuscularly on an outpatient basis. The mean time required for clinical symptoms (throat pain, dysphagia and fever) to resolve was compared. No statistically significant difference was found between the clinical recoveries of patients using either antibiotic (P > 0.05). The authors conclude that intramuscular procaine penicillin can be safely prescribed on an outpatient basis to most patients with peritonsillar abscess after incision and drainage. In contrast, a broader spectrum and more expensive antibiotic, such as sulbactam-ampicillin, should be reserved for non-responders.