Evaluation of the impact on different types of human cancer cell of lichen secondary compounds Liken sekonder bileşiklerinin farkli insan kanser hücre tipleri üzerine antikanserojenik etkisi

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Özenoǧlu S., Aydoǧdu G., Dinçsoy A. B., Taghidizaj A. A., Derici K., YILMAZ E., ...More

Turk Hijyen ve Deneysel Biyoloji Dergisi, vol.70, no.4, pp.215-226, 2013 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 70 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.5505/turkhijyen.2013.37167
  • Journal Name: Turk Hijyen ve Deneysel Biyoloji Dergisi
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.215-226
  • Keywords: Anticancer activity, Cancer cells, Lichen metabolites
  • Hacettepe University Affiliated: No


Today, cancer is appearing as a major unsolved health problem. Basicly, surgery, chemotherapy and hormone therapy models are used in the treatment of cancer. Basic procedures and drugs used in the treatment of cancer are thought to be insufficient. These treatments have some side effects and they take a long time. Due to the problems encountered in the treatment of cancer in the recent years, alternative methods of treatment are being researched. For this purpose the effect of herbal, synthetic and fungus organisms against various types of cancer is being investigated. As a result of these investigations, lichens and their secondary metabolites are also proposed to be used as an alternative method in cancer treatment. Lichens are a symbiotic association of a fungus and a photosynthetic partner. These metabolites were identified as fatty acids, lactons, zeorin, pulvic acid, petroleum, depsids, depsidons and antrokinon derivatives. Impact of lichen secondary compound studies on different human cancer types, aims to find a promising drug Candidate molecule.