Enhanced serum levels of matrix Gla protein and bone morphogenetic protein in acute coronary syndrome patients

Buyukterzi, Zafer; Can, Ummugulsum; Alpaydin, Sertac; Guzelant, Asuman; Karaarslan, Sukru; Mustu, Mehmet; KOÇYİĞİT, DUYGU; Gurses, Kadri

doi:10.1002/jcla.22278

Enhanced serum levels of matrix Gla protein and bone morphogenetic protein in acute coronary syndrome patients

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Buyukterzi Z., Can U., Alpaydin S., Guzelant A., Karaarslan S., Mustu M., ...More

JOURNAL OF CLINICAL LABORATORY ANALYSIS, vol.32, no.3, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 32 Issue: 3
Publication Date: 2018
Doi Number: 10.1002/jcla.22278
Journal Name: JOURNAL OF CLINICAL LABORATORY ANALYSIS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe University Affiliated: Yes

Abstract

BackgroundVascular calcification has been found to be associated with increased risk of cardiovascular (CV) morbidity and mortality. Various bone-associated proteins have been suggested to be related with this process. In this study, we aimed to evaluate whether serum levels of bone morphogenic protein-4 (BMP-4) and matrix Gla protein (MGP) differed in patients who were found to have normal epicardial coronary arteries or a culprit lesion in the coronary angiography leading to acute coronary syndrome (ACS).