Enhanced serum levels of matrix Gla protein and bone morphogenetic protein in acute coronary syndrome patients

Buyukterzi Z., Can U., Alpaydin S., Guzelant A., Karaarslan S., Mustu M., ...More

JOURNAL OF CLINICAL LABORATORY ANALYSIS, vol.32, no.3, 2018 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.1002/jcla.22278
  • Journal Name: JOURNAL OF CLINICAL LABORATORY ANALYSIS
  • Journal Indexes: Science Citation Index Expanded, Scopus

Abstract

BackgroundVascular calcification has been found to be associated with increased risk of cardiovascular (CV) morbidity and mortality. Various bone-associated proteins have been suggested to be related with this process. In this study, we aimed to evaluate whether serum levels of bone morphogenic protein-4 (BMP-4) and matrix Gla protein (MGP) differed in patients who were found to have normal epicardial coronary arteries or a culprit lesion in the coronary angiography leading to acute coronary syndrome (ACS).