Enhanced serum levels of matrix Gla protein and bone morphogenetic protein in acute coronary syndrome patients

Buyukterzi, Zafer; Can, Ummugulsum; Alpaydin, Sertac; Guzelant, Asuman; Karaarslan, Sukru; Mustu, Mehmet; KOÇYİĞİT, DUYGU; Gurses, Kadri

doi:10.1002/jcla.22278

Enhanced serum levels of matrix Gla protein and bone morphogenetic protein in acute coronary syndrome patients

Buyukterzi Z., Can U., Alpaydin S., Guzelant A., Karaarslan S., Mustu M., ...Daha Fazla

JOURNAL OF CLINICAL LABORATORY ANALYSIS, cilt.32, sa.3, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 32 Sayı: 3
Basım Tarihi: 2018
Doi Numarası: 10.1002/jcla.22278
Dergi Adı: JOURNAL OF CLINICAL LABORATORY ANALYSIS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe Üniversitesi Adresli: Evet

Özet

BackgroundVascular calcification has been found to be associated with increased risk of cardiovascular (CV) morbidity and mortality. Various bone-associated proteins have been suggested to be related with this process. In this study, we aimed to evaluate whether serum levels of bone morphogenic protein-4 (BMP-4) and matrix Gla protein (MGP) differed in patients who were found to have normal epicardial coronary arteries or a culprit lesion in the coronary angiography leading to acute coronary syndrome (ACS).