Enhanced serum levels of matrix Gla protein and bone morphogenetic protein in acute coronary syndrome patients

Buyukterzi, Zafer; Can, Ummugulsum; Alpaydin, Sertac; Guzelant, Asuman; Karaarslan, Sukru; Mustu, Mehmet; KOÇYİĞİT, DUYGU; Gurses, Kadri

doi:10.1002/jcla.22278

Enhanced serum levels of matrix Gla protein and bone morphogenetic protein in acute coronary syndrome patients

Buyukterzi Z., Can U., Alpaydin S., Guzelant A., Karaarslan S., Mustu M., ...More

JOURNAL OF CLINICAL LABORATORY ANALYSIS, vol.32, no.3, 2018 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 32 Issue: 3
Publication Date: 2018
Doi Number: 10.1002/jcla.22278
Journal Name: JOURNAL OF CLINICAL LABORATORY ANALYSIS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe University Affiliated: Yes

Abstract

BackgroundVascular calcification has been found to be associated with increased risk of cardiovascular (CV) morbidity and mortality. Various bone-associated proteins have been suggested to be related with this process. In this study, we aimed to evaluate whether serum levels of bone morphogenic protein-4 (BMP-4) and matrix Gla protein (MGP) differed in patients who were found to have normal epicardial coronary arteries or a culprit lesion in the coronary angiography leading to acute coronary syndrome (ACS).