CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer

Esteva, Francisco; Wang, Jing; Lin, Feng; Mejia, Jaime; Yan, Kai; Altundag, Kadri; Valero, Vicente; Buzdar, Aman; Hortobagyi, Gabriel; Symmans, W.; Pusztai, Lajos

doi:10.1186/bcr1836

CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer

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Esteva F. J., Wang J., Lin F., Mejia J. A., Yan K., Altundag K., ...More

BREAST CANCER RESEARCH, vol.9, no.6, 2007 (SCI-Expanded)

Publication Type: Article / Article
Volume: 9 Issue: 6
Publication Date: 2007
Doi Number: 10.1186/bcr1836
Journal Name: BREAST CANCER RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe University Affiliated: Yes

Abstract

Introduction We performed gene expression analysis to identify molecular predictors of resistance to preoperative concomitant trastuzumab and paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide (T/FEC).