Is serum high-mobility group box 1 (HMGB-1) level correlated with liver fibrosis in chronic hepatitis B?

İNKAYA A. Ç., Demir N. A., Kolgelier S., Sumer S., Demir L. S., Ural O., ...More

MEDICINE, vol.96, no.36, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 96 Issue: 36
  • Publication Date: 2017
  • Doi Number: 10.1097/md.0000000000007547
  • Journal Name: MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: alarmin molecules, chronic hepatitis B, high-mobility group box 1, liver fibrosis, STELLATE CELLS, VIRUS INFECTION, PROTEIN, FAILURE, ALARMINS, MARKER, INJURY
  • Hacettepe University Affiliated: Yes

Abstract

Background: High-mobility group box 1 (HMGB1), identified as an alarmin molecule, was shown to have a role in virus-triggered liver injury. We aimed to evaluate the association between serum levels of HMGB1 and liver fibrosis.