Is serum high-mobility group box 1 (HMGB-1) level correlated with liver fibrosis in chronic hepatitis B?

İNKAYA, AHMET; Demir, Nazlim; Kolgelier, Servet; Sumer, Sua; Demir, Lutfi; Ural, Onur; PEHLIVAN, Fatma; Aslan, Mahmure; Arpaci, Abdullah

doi:10.1097/md.0000000000007547

Is serum high-mobility group box 1 (HMGB-1) level correlated with liver fibrosis in chronic hepatitis B?

İNKAYA A. Ç., Demir N. A., Kolgelier S., Sumer S., Demir L. S., Ural O., ...Daha Fazla

MEDICINE, cilt.96, sa.36, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 96 Sayı: 36
Basım Tarihi: 2017
Doi Numarası: 10.1097/md.0000000000007547
Dergi Adı: MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: alarmin molecules, chronic hepatitis B, high-mobility group box 1, liver fibrosis, STELLATE CELLS, VIRUS INFECTION, PROTEIN, FAILURE, ALARMINS, MARKER, INJURY
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: High-mobility group box 1 (HMGB1), identified as an alarmin molecule, was shown to have a role in virus-triggered liver injury. We aimed to evaluate the association between serum levels of HMGB1 and liver fibrosis.