The role of CD14 gene promoter polymorphism in tuberculosis susceptibility


Ayaslioglu E., Kalpaklioglu F., Kavut A. B. , ERTÜRK A., ÇAPAN N., BİRBEN E.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, cilt.46, ss.158-163, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 46 Konu: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.jmii.2012.05.008
  • Dergi Adı: JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
  • Sayfa Sayıları: ss.158-163

Özet

Background: CD14 is expressed principally by cells of monocyte/macrophage lineage and plays a pivotal role in the innate immunity to intracellular infections. Recent research findings have revealed an association between the CD14 gene promoter polymorphism and several major infectious diseases. Objective: The aim of the present study was to investigate the association between the CD14-159C/T polymorphism and tuberculosis in a Turkish population.