Paradoxical deterioration during the course of antituberculous treatment
JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, vol.98, no.6, pp.954-955, 2006 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 98 Issue: 6
- Publication Date: 2006
- Journal Name: JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.954-955
- Hacettepe University Affiliated: Yes
Abstract
Paradoxical deterioration during antituberculous therapy is defined as the clinical or radiological worsening of pre-existing tuberculous lesions or the development of new lesions in a patient who initially improves. Although it has frequently been reported for patients infected with human immunodeficiency virus (HIV), it can also be seen in HIV-negative patients. Here, we present a case of miliary tuberculosis in a patient who clinically deteriorates after antituberculous treatment, and discuss this confusing entity under the light of the pertinent literature.