Research Information System
in: Periodic and Non-Periodic Fevers, Rolando Cimaz, Editor, Springer, London/Berlin , Milan, pp.161-176, 2020
Behçet disease (BD) is a vasculitis that can affect arteries or veins of any size; thus, it was recently reclassified as a variable vessel vasculitis. BD is characterized by recurrent oral and/or genital ulcers accompanied by ocular, cutaneous, articular, gastrointestinal, and/or central nervous system inflammatory lesions [1]. Hulusi Behçet, a Turkish dermatologist, had described three major signs (oral aphthae, genital ulcerations, and uveitis) of BD in 1937 and defined it as a “triple symptom complex” [2]. There are also reports about BD description in the fifth century BC in the “Third Book of Endemic Diseases [3].”