Cemiplimab monotherapy for first-line treatment of advanced non-small-cell lung cancer with PD-L1 of at least 50%: a multicentre, open-label, global, phase 3, randomised, controlled trial

Sezer, Ahmet; KILIÇKAP, SAADETTİN; GÜMÜŞ, MAHMUT; Bondarenko, Igor; ÖZGÜROĞLU, Mustafa; Gogishvili, Miranda; TÜRK, HACI; ÇİÇİN, İRFAN; Bentsion, Dmitry; Gladkov, Oleg; Clingan, Philip; Sriuranpong, Virote; Rizvi, Naiyer; Gao, Bo; Li, Siyu; Lee, Sue; McGuire, Kristina; Chen, Chieh-; Makharadze, Tamta; PAYDAŞ, SEMRA; Nechaeva, Marina; Seebach, Frank; Weinreich, David; Yancopoulos, George; Gullo, Giuseppe; Lowy, Israel; Rietschel, Petra

doi:10.1016/s0140-6736(21)00228-2

Cemiplimab monotherapy for first-line treatment of advanced non-small-cell lung cancer with PD-L1 of at least 50%: a multicentre, open-label, global, phase 3, randomised, controlled trial

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Sezer A., KILIÇKAP S., GÜMÜŞ M., Bondarenko I., ÖZGÜROĞLU M., Gogishvili M., ...More

LANCET, vol.397, no.10274, pp.592-604, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 397 Issue: 10274
Publication Date: 2021
Doi Number: 10.1016/s0140-6736(21)00228-2
Journal Name: LANCET
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Psycinfo, Veterinary Science Database
Page Numbers: pp.592-604
Hacettepe University Affiliated: Yes

Abstract

Background We aimed to examine cemiplimab, a programmed cell death 1 inhibitor, in the first-line treatment of advanced non-small-cell lung cancer with programmed cell death ligand 1 (PD-L1) of at least 50%.