In vitro activities of new quinolones against Brucella melitensis isolated in a tertiary-care hospital in Turkey

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Kocagoz S., Akova M., Altun B., Gur D., Hascelik G.

CLINICAL MICROBIOLOGY AND INFECTION, vol.8, no.4, pp.240-242, 2002 (SCI-Expanded) identifier identifier


We have evaluated the in vitro activities of seven fluoroquinolones against 69 strains of Brucella melitensis . According to their minimum inhibitory concentration for 90% growth (MIC90 ) values, the most active agent was found to be sparfloxacin (MIC90 0.12 mg/L) followed by levofloxacin, ciprofloxacin, ofloxacin (MIC90 0.50 mg/L) and grepafloxacin (MIC90 1 mg/L), gemifloxacin (MIC90 2 mg/L) and gatifloxacin (MIC90 4 mg/L).