In vitro activities of new quinolones against Brucella melitensis isolated in a tertiary-care hospital in Turkey

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Kocagoz S., Akova M., Altun B., Gur D., Hascelik G.

CLINICAL MICROBIOLOGY AND INFECTION, vol.8, no.4, pp.240-242, 2002 (SCI-Expanded, Scopus)

• Publication Type: Article / Article
• Volume: 8 Issue: 4
• Publication Date: 2002
• Doi Number: 10.1046/j.1469-0691.2002.00416.x
• Journal Name: CLINICAL MICROBIOLOGY AND INFECTION
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.240-242
• Open Archive Collection: AVESIS Open Access Collection
• Hacettepe University Affiliated: Yes

Abstract

We have evaluated the in vitro activities of seven fluoroquinolones against 69 strains of Brucella melitensis . According to their minimum inhibitory concentration for 90% growth (MIC90 ) values, the most active agent was found to be sparfloxacin (MIC90 0.12 mg/L) followed by levofloxacin, ciprofloxacin, ofloxacin (MIC90 0.50 mg/L) and grepafloxacin (MIC90 1 mg/L), gemifloxacin (MIC90 2 mg/L) and gatifloxacin (MIC90 4 mg/L).