Comparison of acute hemodyamic effects of aerosolized and intravenous iloprost in secondary pulmonary hypertension in children with congential heart disease

Hallioglu O., Dilber E., Celiker A.

AMERICAN JOURNAL OF CARDIOLOGY, vol.92, no.8, pp.1007-1009, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 92 Issue: 8
  • Publication Date: 2003
  • Doi Number: 10.1016/s0002-9149(03)00991-3
  • Journal Name: AMERICAN JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1007-1009
  • Hacettepe University Affiliated: No

Abstract

Both aerosolized and intravenous infusion of iloprost caused a significant decrease in mean pulmonary artery pressure and pulmonary vascular resistance. Although intravenous infusion caused a large decrease in mean systemic arterial pressure, this was only slightly affected by aerosolized iloprost. Aerosolized iloprost caused a significant decrease in the pulmonary-to-systemic vascular resistance ratio; however, intravenous infusion did not cause a prominent decrease in this ratio. (C) 2003 by Excerpta Medica, Inc.