PEDIATRIC NEPHROLOGY, vol.33, no.8, pp.1395-1403, 2018 (Peer-Reviewed Journal)
Article / Article
Science Citation Index Expanded, Scopus
Atypical hemolytic uremic syndrome, Children, Neurological involvement, Extrarenal involvement, Eculizumab, ECULIZUMAB, COMPLEMENT, MUTATIONS, INVOLVEMENT
Atypical hemolytic uremic syndrome (aHUS) is a chronic disease characterized by thrombotic microangiopathy and a high risk of end-stage kidney disease. Dysregulation and/or excessive activation of the complement system results in thrombotic microangiopathy. Interest in extrarenal manifestations of aHUS is increasing. This study aimed to determine the clinical characteristics of patients with extrarenal manifestations of aHUS in childhood.