Extra-Renal manifestations of atypical hemolytic uremic syndrome in children

Fidan K., Goknar N., GÜLHAN B., MELEK E., Yildirim Z. Y., Baskin E., ...Daha Fazla

PEDIATRIC NEPHROLOGY, cilt.33, sa.8, ss.1395-1403, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 8
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s00467-018-3933-3
  • Dergi Adı: PEDIATRIC NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1395-1403
  • Anahtar Kelimeler: Atypical hemolytic uremic syndrome, Children, Neurological involvement, Extrarenal involvement, Eculizumab, ECULIZUMAB, COMPLEMENT, MUTATIONS, INVOLVEMENT
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Atypical hemolytic uremic syndrome (aHUS) is a chronic disease characterized by thrombotic microangiopathy and a high risk of end-stage kidney disease. Dysregulation and/or excessive activation of the complement system results in thrombotic microangiopathy. Interest in extrarenal manifestations of aHUS is increasing. This study aimed to determine the clinical characteristics of patients with extrarenal manifestations of aHUS in childhood.