Convalescent (immune) plasma treatment in a myelodysplastic COVID-19 patient with disseminated tuberculosis.


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Çınar O., Sayınalp B., Aladağ K., Avşar K., Velet M., İnkaya A. Ç., ...More

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, vol.59, pp.102821, 2020 (SCI-Expanded) identifier identifier identifier

Abstract

During the ongoing COVID-19 pandemic due to the SARS-CoV-2 virus of which evidence-based medical paradigms cannot be easily applied; difficult clinical decisions shall be required particularly in the 'difficult-to-treat' cases of high risk group with associated comorbidities. Convalescent immune plasma therapy is a promising option as a sort of 'rescue' treatment in COVID-19 immune syndrome, where miraculous antiviral drugs are not available yet. In this report, we aim to convey our experience of multi-task treatment approach with convalescent immune plasma and anti-cytokine drug combination in a COVID-19 patient with extremely challenging comorbidities including active myeloid malignancy, disseminated tuberculosis and kidney failure.