Current status of micro/nanomotors in drug delivery

Tezel G., TİMUR S. S., KURALAY F., GÜRSOY R. N., ULUBAYRAM K., ÖNER L., ...Daha Fazla

JOURNAL OF DRUG TARGETING, cilt.29, sa.1, ss.29-45, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 29 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1080/1061186x.2020.1797052
  • Dergi Adı: JOURNAL OF DRUG TARGETING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Chemical Abstracts Core, EMBASE, International Pharmaceutical Abstracts, MEDLINE
  • Sayfa Sayıları: ss.29-45
  • Anahtar Kelimeler: Micro, nanomotor, propulsion, drug delivery, nanotechnology, biodegradation, SOLID LIPID NANOPARTICLES, STOMATOCYTE NANOMOTORS, INTRACELLULAR DELIVERY, CATALYTIC NANOMOTORS, MICROMOTORS DRIVEN, AUTONOMOUS MOTION, JANUS MICROMOTORS, SILICA NANOMOTORS, HYALURONIC-ACID, NANO-MOTORS
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Synthetic micro/nanomotors (MNMs) are novel, self-propelled nano or microscale devices that are widely used in drug transport, cell stimulation and isolation, bio-imaging, diagnostic and monitoring, sensing, photocatalysis and environmental remediation. Various preparation methods and propulsion mechanisms make MNMs "tailormade" nanosystems for the intended purpose or use. As the one of the newest members of nano carriers, MNMs open a new perspective especially for rapid drug transport and gene delivery. Although there exists limited number ofin-vivostudies for drug delivery purposes, existence ofin-vitrosupportive data strongly encourages researchers to move on in this field and benefit from the manoeuvre capability of these novel systems. In this article, we reviewed the preparation and propulsion mechanisms of nanomotors in various fields with special attention to drug delivery systems.