Histopathological Diagnosis of Mycosis Fungoides
TURK DERMATOLOJI DERGISI-TURKISH JOURNAL OF DERMATOLOGY, vol.19, no.1, pp.27-35, 2025 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Review
- Volume: 19 Issue: 1
- Publication Date: 2025
- Doi Number: 10.4274/tjd.galenos.2025.03521
- Journal Name: TURK DERMATOLOJI DERGISI-TURKISH JOURNAL OF DERMATOLOGY
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, TR DİZİN (ULAKBİM)
- Page Numbers: pp.27-35
- Open Archive Collection: AVESIS Open Access Collection
- Hacettepe University Affiliated: Yes
Abstract
Mycosis fungoides (MF) is a neoplastic proliferation characterized by cutaneous infiltration of atypical T-lymphocytes. MF often shows diagnostic difficulties. Histopathology, immunochemistry, and clonality determination may be an auxiliary diagnostic method but they are not always sufficient and the final diagnosis should be made with correlation of clinical findings, routine histopathology, immunohistochemistry, and gene rearrangement studies. Histopathological findings may also vary in different stages of the disease. In this article, the histopathological findings of classical MF and its variants are reviewed together with their immunohistochemical features.