Elevated M2-muscarinic and beta 1-adrenergic receptor autoantibody levels are associated with paroxysmal atrial fibrillation

Yalcin M. U., GÜRSES K. M., KOÇYİĞİT D., KESİKLİ S. A., Ates A. H., EVRANOS B., ...Daha Fazla

CLINICAL RESEARCH IN CARDIOLOGY, cilt.104, sa.3, ss.226-233, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 104 Sayı: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s00392-014-0776-1
  • Dergi Adı: CLINICAL RESEARCH IN CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.226-233
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Pathophysiologic mechanisms underlying lone atrial fibrillation (AF) have not been clearly demonstrated yet. Emerging evidence has indicated that autoimmunity may play a role in the development of AF. Relationship between serum anti-M2-muscarinic receptor autoantibody (anti-M2-R) and anti-beta 1-adrenergic receptor autoantibody (anti-beta 1-R) levels and lone paroxysmal atrial fibrillation (PAF) has not been investigated. We aimed to compare anti-M2-R and anti-beta 1-R levels between lone PAF patients and healthy control subjects.