Elevated M2-muscarinic and beta 1-adrenergic receptor autoantibody levels are associated with paroxysmal atrial fibrillation


Yalcin M. U. , GÜRSES K. M. , KOÇYİĞİT D., KESİKLİ S. A. , Ates A. H. , EVRANOS B., ...More

CLINICAL RESEARCH IN CARDIOLOGY, vol.104, no.3, pp.226-233, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 104 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.1007/s00392-014-0776-1
  • Journal Name: CLINICAL RESEARCH IN CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.226-233

Abstract

Pathophysiologic mechanisms underlying lone atrial fibrillation (AF) have not been clearly demonstrated yet. Emerging evidence has indicated that autoimmunity may play a role in the development of AF. Relationship between serum anti-M2-muscarinic receptor autoantibody (anti-M2-R) and anti-beta 1-adrenergic receptor autoantibody (anti-beta 1-R) levels and lone paroxysmal atrial fibrillation (PAF) has not been investigated. We aimed to compare anti-M2-R and anti-beta 1-R levels between lone PAF patients and healthy control subjects.