Trojanosides I-K: New cycloartane-type glycosides from the aerial parts of Astragalus trojanus

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Bedir E., Tatli İ. İ., Calis I., Khan I.

CHEMICAL & PHARMACEUTICAL BULLETIN, vol.49, no.11, pp.1482-1486, 2001 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 11
  • Publication Date: 2001
  • Doi Number: 10.1248/cpb.49.1482
  • Journal Name: CHEMICAL & PHARMACEUTICAL BULLETIN
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1482-1486
  • Hacettepe University Affiliated: Yes

Abstract

Three new cycloartane-type triterpene glycosides have been isolated from the aerial parts of Astragalus trojanus. The structures were established mainly by a combination of one- and two-dimensional NMR techniques [H-1-H-1-correlation spectroscopy (COSY), H-1-C-13-heteronuclear multiple quantum correlation spectroscopy (HMQC), and H-1-C-13-heteronuclear multiple-bond correlation spectroscopy (HMBC)] and high resolution electrospray ionization mass spectrometry (HR-ESI-MS) as 3-O-beta-(2',3'-di-O-acetyl)-D-xylopyranosyl-6-O-beta -D-glucopyranosyl-16-O-acetoxy-20(R),24(S)-epoxycycloartane-3 beta ,6 alpha ,16 beta ,25-tetrol, 3-O-[alpha -L-rhamnopyranosyl-(1 -->2)beta-(3',4'-di-O-acetyl)-D-xylopyranosyl]-6-O-beta -D-xylop'ranosyl-20(R),24(S)-epox3-cycloai-tane-3p,6a,16P,25-tetrol, 3-O-beta -D-xylopyranosyl-6,16-di-O-beta -D-glucopyranosyl-20(R),24(S)-epoxycycloartane-3 beta ,6 alpha ,16 beta ,25-tetrol.