Durable remission of leptomeningeal metastases from hormone-responsive prostate cancer

Zhang M., Mahta A., Kim R. Y., Akar S., Kesari S.

MEDICAL ONCOLOGY, vol.29, no.2, pp.806-808, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 29 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1007/s12032-011-9906-z
  • Journal Name: MEDICAL ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.806-808
  • Hacettepe University Affiliated: Yes


Prostate cancer is rarely associated with leptomeningeal metastasis. An 87-year-old man with a history of prostate cancer presented with leptomeningeal metastasis. He received hormonal therapy with leuprolide. Subsequently, he achieved an impressive response, indicated by a constant fall in his PSA levels and by the stabilization of leptomeningeal disease and clinical improvement. Hormonal therapy may be effective in inducing remission in hormone-sensitive prostate cancer with leptomeningeal metastasis.