Diabetes mellitus and insulin resistance in mothers, fathers, sisters, and brothers of women with polycystic ovary syndrome: a systematic review and meta-analysis

YILMAZ B., Vellanki P., Ata B., Yildiz B. O.

FERTILITY AND STERILITY, vol.110, no.3, pp.523-547, 2018 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 110 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.1016/j.fertnstert.2018.04.024
  • Journal Name: FERTILITY AND STERILITY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.523-547
  • Keywords: Diabetes mellitus, first-degree relatives, insulin resistance, meta-analysis, polycystic ovary syndrome, systematic review, IMPAIRED GLUCOSE-TOLERANCE, GENOME-WIDE ASSOCIATION, FIRST-DEGREE RELATIVES, BETA-CELL DYSFUNCTION, 1ST DEGREE RELATIVES, 1ST-DEGREE RELATIVES, FAMILY-HISTORY, METABOLIC SYNDROME, DEHYDROEPIANDROSTERONE-SULFATE, CARDIOVASCULAR-DISEASE

Abstract

Objective(s): To analyze whether first-degree relatives (FDR) of patients with polysystic ovary syndrome (PCOS) have an increased risk of insulin resistance and glucose intolerance.