Inhibiting inducible nitric oxide synthase with rutin reduces renal ischemia/reperfusion injury
CANADIAN JOURNAL OF SURGERY, cilt.56, sa.1, ss.6-14, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 56 Sayı: 1
- Basım Tarihi: 2013
- Doi Numarası: 10.1503/cjs.004811
- Dergi Adı: CANADIAN JOURNAL OF SURGERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.6-14
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Hacettepe Üniversitesi Adresli: Evet
Özet
Background: Nitric oxide (NO) seems to play an important role during renal ischemia/reperfusion (I/R) injury. We investigated whether rutin inhibits inducible nitric oxide synthase (iNOS) and reduces 3-nitrotyrosine (3-NT) formation in the kidneys of rats during I/R.