Inhibiting inducible nitric oxide synthase with rutin reduces renal ischemia/reperfusion injury

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Korkmaz A., KOLANKAYA D.

CANADIAN JOURNAL OF SURGERY, cilt.56, sa.1, ss.6-14, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1503/cjs.004811
  • Dergi Adı: CANADIAN JOURNAL OF SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.6-14
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Nitric oxide (NO) seems to play an important role during renal ischemia/reperfusion (I/R) injury. We investigated whether rutin inhibits inducible nitric oxide synthase (iNOS) and reduces 3-nitrotyrosine (3-NT) formation in the kidneys of rats during I/R.