Inhibiting inducible nitric oxide synthase with rutin reduces renal ischemia/reperfusion injury

Korkmaz A., KOLANKAYA D.

CANADIAN JOURNAL OF SURGERY, cilt.56, ss.6-14, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 56 Konu: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1503/cjs.004811
  • Dergi Adı: CANADIAN JOURNAL OF SURGERY
  • Sayfa Sayıları: ss.6-14

Özet

Background: Nitric oxide (NO) seems to play an important role during renal ischemia/reperfusion (I/R) injury. We investigated whether rutin inhibits inducible nitric oxide synthase (iNOS) and reduces 3-nitrotyrosine (3-NT) formation in the kidneys of rats during I/R.