Serum vitamin-E levels and its relation to clinical features in nonalcoholic fatty liver disease with elevated ALT levels

Cankurtaran, M; Kav, T; DOĞU, BURCU; Shorbagi, A; HALİL, MELTEM; Coskun, T; Arslan, S

Serum vitamin-E levels and its relation to clinical features in nonalcoholic fatty liver disease with elevated ALT levels

Cankurtaran M., Kav T., DOĞU B. B., Shorbagi A., HALİL M. G., Coskun T., ...Daha Fazla

ACTA GASTRO-ENTEROLOGICA BELGICA, cilt.69, sa.1, ss.5-11, 2006 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 69 Sayı: 1
Basım Tarihi: 2006
Dergi Adı: ACTA GASTRO-ENTEROLOGICA BELGICA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
Sayfa Sayıları: ss.5-11
Hacettepe Üniversitesi Adresli: Hayır

Özet

Background: Oxidative stress and free oxygen radicals play an important role in the progression from simple fatty liver to steato-hepatitis. Deficiency of antioxidants like vitamin-E has been reported to trigger this progression. The main aims of our study were to measure plasma vitamin-E levels in nonalcoholic fatty liver disease (NAFLD), to explain its relationship with biochemical parameters and to examine the possible therapeutic and prophylactic role of vitamin-E.