Crystal structure of 3,3-dichloro-N-p-methoxyphenyl-4-(2-phenyistryl)-2-azetidinone

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Kabak M., Guner V., Elerman Y., Durlu T.

ANALYTICAL SCIENCES, cilt.19, sa.6, ss.969-970, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 6
  • Basım Tarihi: 2003
  • Doi Numarası: 10.2116/analsci.19.969
  • Dergi Adı: ANALYTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.969-970
  • Hacettepe Üniversitesi Adresli: Evet

Özet

3.3-Dichloro-N-p-methoxyphenyl-4-(2-phenylstryl)-2-azetidinone (C22H15Cl2NO2) was studied by X-Ray analysis, which indicated a monoclinic space group, P2(1)/c, with a = 9.619(5), b = 13.879(4), c = 14.161(5)Angstrom, beta = 100. 16(3)degrees, V = 1860.8(13)Angstrom(3), Z = 4, D-c = 1.414 g cm(-3), mu(Mo K-a) = 0.366 mm(-1) and F-000 = 816. The structure was solved by direct methods and refined to R = 0.041 for 4026 reflections [I > 2sigma(I). The beta-lactam ring (2-azetidinone) has antimicrobial affects. The substituents of the methoxyphenyl and phenyl substituents do not change the activity property of the betalactam ring, and the activity properties depend on the planarity of the beta-lactam ring.