Factor V 1691 G-A (Leiden) polymorphism and cancer-related venous thromboembolism: a meta-analysis of published studies

Eroglu A., KARASOY D., Eroglu N., Akar N.

JOURNAL OF BUON, cilt.13, sa.1, ss.61-64, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 1
  • Basım Tarihi: 2008
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.61-64
  • Anahtar Kelimeler: cancer, factor V Leiden, meta-analysis, thrombosis, FACTOR-V-LEIDEN, ACTIVATED PROTEIN-C, ONCOLOGY PATIENTS, BLOOD-DONORS, MUTATION, THROMBOSIS, PREVALENCE, RESISTANCE, RISK, G20210A
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Purpose: Although one of the most common genetic polymorphisms that predispose to venous thromboembolism (VTE) is factor V 1691 G-A (Factor V Leiden; FVL), the effect of this polymorphism on the development of VTE in cancer patients is unclear We have therefore performed a meta-analysis to estimate the risk of VTE associated with FVL among cancer patients.