Venous ulcerations due to inherited fibrinogen disorder in two male siblings


Yildirim S. K. , ELÇİN G. , BÜYÜKAŞIK Y.

TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY, vol.50, no.3, pp.131-134, 2016 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.4274/turkderm.72687
  • Title of Journal : TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY
  • Page Numbers: pp.131-134

Abstract

Inherited fibrinogen disorders are a group of diseases for which decreased fibrinogen levels and/or decreased activity or abnormal functional activity are responsible. These diseases can be asymptomatic or manifesting as bleeding or thrombosis. Although hypercoagulopathic conditions are listed as causes of lower leg ulcerations, inherited fibrinogen disorders are rarely reported as causes of lower leg ulcerations in the literature. Here, we describe two siblings who had recurrent lower leg ulcerations due to inherited fibrinogen disorder. In cases of recurrent venous ulcerations which are not due to common etiologies and have familial history, it should be kept in mind that there may be an underlying inherited fibrinogen disorder as a rare reason for the hypercogulopathic condition.