The platelet to lymphocyte ratio predicts overall survival better than the neutrophil to lymphocyte ratio in metastatic renal cell carcinoma.


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Aktepe O. H. , GÜner G., GÜven D. C. , Şahİn T. K. , ArdiÇ F. S. , YÜce D., ...More

Turkish journal of medical sciences, vol.51, pp.757-765, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51
  • Publication Date: 2021
  • Doi Number: 10.3906/sag-2009-75
  • Title of Journal : Turkish journal of medical sciences
  • Page Numbers: pp.757-765
  • Keywords: NLR, PLR, metastatic renal cell carcinoma, prognosis, tyrosine kinase inhibitors, PRETREATMENT NEUTROPHIL, PROGNOSTIC VALUE, POOR-PROGNOSIS, CANCER, INFLAMMATION, INFILTRATION, ASSOCIATION, EXPRESSION, COHORT, GRADE

Abstract

Background/aim: The prognostic values of systemic inflammatory markers, neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR) on overall survival (OS) of metastatic renal cell carcinoma patients (mRCC) treated with tyrosine kinase inhibitors (TKI) remain unclear. Thus, the present study aimed to investigate the prognostic impact of these markers on OS of mRCC patients.