Synthesis, crystal structure and Hirshfeld surface analysis of 5-oxo-<i>N</i>-phenyl-3-(thiophen-2-yl)-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-carboxamide

Aliyeva, Khatira; HÖKELEK, TUNCER; Khrustalev, Victor; Rzayev, Rövnəq; Bhattarai, Ajaya; Maharramov, Abel; Shikhaliyev, Namig

doi:10.1107/s205698902500057x

Synthesis, crystal structure and Hirshfeld surface analysis of 5-oxo-<i>N</i>-phenyl-3-(thiophen-2-yl)-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-carboxamide

Aliyeva K. N., HÖKELEK T., Khrustalev V. N., Rzayev R., Bhattarai A., Maharramov A. M., ...Daha Fazla

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, ss.177-193, 2025 (ESCI)

Yayın Türü: Makale / Tam Makale
Basım Tarihi: 2025
Doi Numarası: 10.1107/s205698902500057x
Dergi Adı: ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
Sayfa Sayıları: ss.177-193
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

The asymmetric unit of the title compound, C23H19NO2S, contains two molecules that differ in the conformation of the two carboxamide moieties. In the crystal, intermolecular N-H center dot center dot center dot O hydrogen bonds link the molecules into chains propagating parallel to the c-axis direction. Between the molecules, weak C-H center dot center dot center dot pi(ring) interactions are present, whereas pi-pi interactions are not observed. The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions to the crystal packing are from H center dot center dot center dot H (47.6%), H center dot center dot center dot C/C center dot center dot center dot H (33.4%) and H center dot center dot center dot O/O center dot center dot center dot H (11.6%) interactions. Orientational disorder is observed for both thiophene rings.