In the title complex, [Ni(C8H5O3)(2)(C6H6N2O)(2)(H2O)(2)], the Ni II cation is located on an inversion center and is coordinated by two 4-formylbenzoate (FB) anions, two nicotinamide (NA) ligands and two water molecules. The four O atoms in the equatorial plane around the Ni II cation form a slightly distorted square-planar arrangement, while the slightly distorted octahedral coordination is completed by the two N atoms of the NA ligands in the axial positions. The dihedral angle between the carboxylate group and the adjacent benzene ring is 23.67 (8)(circle), while the pyridine and benzene rings are oriented at an angle of 89.04 (4)(circle). The coordinating water molecule links with the carboxylate group via an OH...O hydrogen bond. In the crystal, N-H..O, O-H...O and weak C-H...O hydrogen bonds link the molecules into a three-dimensional supramolecular network. pi-pi contacts between benzene rings [centroid-centroid distance = 3.8414 (7) angstrom] may further stabilize the structure. A weak C-H ...pi interaction also occurs.