Increased Levels of 25 Hydroxyvitamin D and 1,25-Dihydroxyvitamin D After Rosuvastatin Treatment: A Novel Pleiotropic Effect of Statins?

Yavuz B., Ertugrul D. T., Cil H., Ata N., Akin K. O., Yalcin A. A., ...More

CARDIOVASCULAR DRUGS AND THERAPY, vol.23, no.4, pp.295-299, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 4
  • Publication Date: 2009
  • Doi Number: 10.1007/s10557-009-6181-8
  • Journal Name: CARDIOVASCULAR DRUGS AND THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.295-299
  • Hacettepe University Affiliated: Yes

Abstract

Low levels of 25-hydroxyvitamin D are associated with higher risk of cardiovascular morbidity and mortality. Large trials demonstrated that statins significantly decrease cardiovascular morbidity and mortality. 7-dehydrocholesterol is the precursor of both cholesterol and vitamin D. The aim of this study was to investigate the possible effect of rosuvastatin on vitamin D metabolism.