Clinical significance of ADAMTS1, ADAMTS5, ADAMTS9 aggrecanases and IL-17A, IL-23, IL-33 cytokines in polycystic ovary syndrome

Karakose M., Demircan K., Tutal E., Demirci T., Arslan M. S., Sahin M., ...More

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, vol.39, no.11, pp.1269-1275, 2016 (SCI-Expanded) identifier identifier identifier


Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) are involved in inflammation and fertility. The aim of this investigation was to evaluate the serum levels of ADAMTS1, ADAMTS5, ADAMTS9, IL-17, IL-23, IL-33 and to find out the relationship between these inflammatory cytokines and ADAMTSs in PCOS patients.