Clinical significance of ADAMTS1, ADAMTS5, ADAMTS9 aggrecanases and IL-17A, IL-23, IL-33 cytokines in polycystic ovary syndrome

Karakose, M.; Demircan, K.; Tutal, E.; Demirci, T.; Arslan, M.; Sahin, M.; Celik, H.; Kazanci, F.; Karakaya, JALE; Cakal, E.; Delibasi, T.

doi:10.1007/s40618-016-0472-2

Clinical significance of ADAMTS1, ADAMTS5, ADAMTS9 aggrecanases and IL-17A, IL-23, IL-33 cytokines in polycystic ovary syndrome

Karakose M., Demircan K., Tutal E., Demirci T., Arslan M. S., Sahin M., ...Daha Fazla

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, cilt.39, sa.11, ss.1269-1275, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 39 Sayı: 11
Basım Tarihi: 2016
Doi Numarası: 10.1007/s40618-016-0472-2
Dergi Adı: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1269-1275
Hacettepe Üniversitesi Adresli: Evet

Özet

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) are involved in inflammation and fertility. The aim of this investigation was to evaluate the serum levels of ADAMTS1, ADAMTS5, ADAMTS9, IL-17, IL-23, IL-33 and to find out the relationship between these inflammatory cytokines and ADAMTSs in PCOS patients.