An experimental study of choleretic effect and histopathologic alterations in the gastrointestinal system after whole-bowel irrigation

Buyukyavuz I., Talim B., Ciftci A., Kale G., Senocak M., Buyukpamukcu N.

JOURNAL OF PEDIATRIC SURGERY, vol.39, no.4, pp.582-586, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 4
  • Publication Date: 2004
  • Doi Number: 10.1016/j.jpedsurg.2003.12.019
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.582-586
  • Hacettepe University Affiliated: Yes


Background/Purpose: Whole-bowel irrigation (WBI) has been used for different purposes. It has been the preferred method of bowel cleansing before large bowel surgery and colonoscopy. There are some studies about histopathologic alterations in the gastrointestinal system caused by WBI. It was reported that large quantities of bile-stained intraluminal fluid were seen after WBI with lactated Ringer's solution. In light of all these studies, the authors have decided to inspect whether WBI is choleretic and whether the histopathologic findings in the gastrointestinal system are caused by this choleretic effect.