Regioselective alkylation of pyrrole with 2-benzylidenemalononitriles catalyzed by Cu(OTf)(2)

Tasgin, Dilek; TEMELLİ, BARIŞ; Yazici, Arife; Aytac, Sertan; ÜNALEROĞLU, CANAN

doi:10.2174/157017808783955763

Regioselective alkylation of pyrrole with 2-benzylidenemalononitriles catalyzed by Cu(OTf)(2)

Tasgin D. I., TEMELLİ B., Yazici A., Aytac S., ÜNALEROĞLU C.

LETTERS IN ORGANIC CHEMISTRY, cilt.5, sa.3, ss.165-168, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 5 Sayı: 3
Basım Tarihi: 2008
Doi Numarası: 10.2174/157017808783955763
Dergi Adı: LETTERS IN ORGANIC CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.165-168
Hacettepe Üniversitesi Adresli: Evet

Özet

Copper triflate was used as catalyst for the addition of pyrrole to 2-benzylidenemalononitrile and its substituted derivatives. 2-Alkylated pyrrole derivatives were regioselectively obtained in mild reaction conditions. The addition reactions were found to be highly dependent on the substituents of the phenyl group.