Regioselective alkylation of pyrrole with 2-benzylidenemalononitriles catalyzed by Cu(OTf)(2)

Tasgin D. I. , TEMELLİ B. , Yazici A., Aytac S., ÜNALEROĞLU C.

LETTERS IN ORGANIC CHEMISTRY, cilt.5, ss.165-168, 2008 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 5 Konu: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.2174/157017808783955763
  • Dergi Adı: LETTERS IN ORGANIC CHEMISTRY
  • Sayfa Sayıları: ss.165-168

Özet

Copper triflate was used as catalyst for the addition of pyrrole to 2-benzylidenemalononitrile and its substituted derivatives. 2-Alkylated pyrrole derivatives were regioselectively obtained in mild reaction conditions. The addition reactions were found to be highly dependent on the substituents of the phenyl group.