Regioselective alkylation of pyrrole with 2-benzylidenemalononitriles catalyzed by Cu(OTf)(2)

Tasgin D. I., TEMELLİ B., Yazici A., Aytac S., ÜNALEROĞLU C.

LETTERS IN ORGANIC CHEMISTRY, vol.5, no.3, pp.165-168, 2008 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 3
  • Publication Date: 2008
  • Doi Number: 10.2174/157017808783955763
  • Journal Name: LETTERS IN ORGANIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.165-168
  • Hacettepe University Affiliated: Yes

Abstract

Copper triflate was used as catalyst for the addition of pyrrole to 2-benzylidenemalononitrile and its substituted derivatives. 2-Alkylated pyrrole derivatives were regioselectively obtained in mild reaction conditions. The addition reactions were found to be highly dependent on the substituents of the phenyl group.