The plasma gelsolin levels in atopic dermatitis: Effect of atopy and disease severity

Gungor H. E., Sahiner Ü. M., KARAKÜKCÜ Ç., Sahiner N., Torun Y. A.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, vol.44, no.3, pp.221-225, 2016 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1016/j.aller.2015.05.005
  • Journal Name: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.221-225
  • Keywords: Apoptosis, Atopic dermatitis, Gelsolin, Inflammation, APOPTOSIS, PROTEINS, ALLERGEN
  • Hacettepe University Affiliated: Yes

Abstract

Background: Gelsolin is an actin-binding protein with several cellular functions including antiapoptosis and is reported to have an anti-inflammatory effect. Apoptosis of keratinocytes has been implicated as a key mechanism of atopic dermatitis (AD).