Joint Modeling Approach on Evaluating Time-Dependent CutOff Values for C-Reactive Protein in Mixed Intensive Care Unit Population
CLINICAL LABORATORY, vol.66, no.9, pp.1725-1730, 2020 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 66 Issue: 9
- Publication Date: 2020
- Doi Number: 10.7754/clin.lab.2020.191239
- Journal Name: CLINICAL LABORATORY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Page Numbers: pp.1725-1730
- Hacettepe University Affiliated: Yes
Abstract
Background: Serial C-reactive protein (CRP) biomarker values are frequently recorded from patients in adult intensive care units (ICU). The aim of this study was to assess the time-dependent diagnostic accuracy of repeated CRP measurements in predicting ICU mortality and determine the time-dependent cutoff values for this biomarker in mixed ICU population.