Joint Modeling Approach on Evaluating Time-Dependent CutOff Values for C-Reactive Protein in Mixed Intensive Care Unit Population

KONAR, NAİME; KARAİSMAİLOĞLU, EDA; PORTAKAL AKÇİN, OYTUN; PINAR, ASLI; DİKMEN, ZELİHA; KARAAĞAOĞLU, AHMET

doi:10.7754/clin.lab.2020.191239

Joint Modeling Approach on Evaluating Time-Dependent CutOff Values for C-Reactive Protein in Mixed Intensive Care Unit Population

KONAR N. M., KARAİSMAİLOĞLU E., PORTAKAL AKÇİN O., PINAR A., DİKMEN Z. G., KARAAĞAOĞLU A. E.

CLINICAL LABORATORY, cilt.66, sa.9, ss.1725-1730, 2020 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 66 Sayı: 9
Basım Tarihi: 2020
Doi Numarası: 10.7754/clin.lab.2020.191239
Dergi Adı: CLINICAL LABORATORY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
Sayfa Sayıları: ss.1725-1730
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Serial C-reactive protein (CRP) biomarker values are frequently recorded from patients in adult intensive care units (ICU). The aim of this study was to assess the time-dependent diagnostic accuracy of repeated CRP measurements in predicting ICU mortality and determine the time-dependent cutoff values for this biomarker in mixed ICU population.