Joint Modeling Approach on Evaluating Time-Dependent CutOff Values for C-Reactive Protein in Mixed Intensive Care Unit Population


KONAR N. M. , KARAİSMAİLOĞLU E., PORTAKAL AKÇİN O. , PINAR A. , DİKMEN Z. G. , KARAAĞAOĞLU A. E.

CLINICAL LABORATORY, vol.66, no.9, pp.1725-1730, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 9
  • Publication Date: 2020
  • Doi Number: 10.7754/clin.lab.2020.191239
  • Title of Journal : CLINICAL LABORATORY
  • Page Numbers: pp.1725-1730

Abstract

Background: Serial C-reactive protein (CRP) biomarker values are frequently recorded from patients in adult intensive care units (ICU). The aim of this study was to assess the time-dependent diagnostic accuracy of repeated CRP measurements in predicting ICU mortality and determine the time-dependent cutoff values for this biomarker in mixed ICU population.