2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients

Sartelli M., Di Bella S., McFarland L. V. , Khanna S., Furuya-Kanamori L., Abuzeid N., ...More

WORLD JOURNAL OF EMERGENCY SURGERY, vol.14, 2019 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 14
  • Publication Date: 2019
  • Doi Number: 10.1186/s13017-019-0228-3
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Keywords: Clostridioides difficile infection, Clostridium difficile infection, Pseudomembranous colitis, Antimicrobial treatment, Fecal microbiota transplantation, Infection control, Antimicrobial stewardship, FECAL MICROBIOTA TRANSPLANTATION, INFLAMMATORY-BOWEL-DISEASE, PROTON-PUMP INHIBITORS, CLINICAL-PRACTICE GUIDELINES, CLINDAMYCIN-ASSOCIATED COLITIS, ANTIBIOTIC-ASSOCIATED DIARRHEA, HEALTH-CARE EPIDEMIOLOGY, LENGTH-OF-STAY, RISK-FACTORS, BINARY TOXIN


In the last three decades, Clostridium difficile infection (CDI) has increased in incidence and severity in many countries worldwide. The increase in CDI incidence has been particularly apparent among surgical patients. Therefore, prevention of CDI and optimization of management in the surgical patient are paramount. An international multidisciplinary panel of experts from the World Society of Emergency Surgery (WSES) updated its guidelines for management of CDI in surgical patients according to the most recent available literature. The update includes recent changes introduced in the management of this infection.