Choroid plexus carcinoma is a malignant intraventricular tumor of childhood with poor prognosis. Complete surgical resection is the most important prognostic factor. Unfortunately, complete resection of the CPC is a challenge for neurosurgeons due to extreme vascularity of the tumor, its large size, and its tendency to make invasion to the adjacent brain parenchyma. Here we present a 24-month-old boy with a triventricular CPC, to whom multi-staged endoscope-assisted microsurgical technique was performed. Complete resection was achieved. Postoperatively patient was improved neurologically and discharged home in stable condition. It is shown that multi-staged endoscope-assisted microsurgical technique definitely help neurosurgeons in dealing with this challenging tumors.