Cardiac Resynchronization Therapy Induces Adaptive Metabolic Transitions in the Metabolomic Profile of Heart Failure

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Nemutlu E., Zhang S., XU Y., TERZIC A., ZHONG L., DZEJA P. D., ...Daha Fazla

JOURNAL OF CARDIAC FAILURE, cilt.21, sa.6, ss.460-469, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.cardfail.2015.04.005
  • Dergi Adı: JOURNAL OF CARDIAC FAILURE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.460-469
  • Anahtar Kelimeler: Heart failure, metabolism, cardiac resynchronization therapy, MYOCARDIAL BLOOD-FLOW, SUBSTRATE METABOLISM, OXYGEN-CONSUMPTION, ACID-METABOLISM, IDENTIFICATION, REVEALS, HUMANS, SPECTROSCOPY, DYSSYNCHRONY, MODULATION
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Heart failure (HF) is associated with ventricular dyssynchrony and energetic inefficiency, which can be alleviated by cardiac resynchronization therapy (CRT). The aim of this study was to determine the metabolomic signature in HF and its prognostic value regarding the response to CRT.