Evaluation of the removal of 2-Hydroxyisocaproic acid from the root canal and its effect on the bond strength of MTA

USTA S. N., EYMİRLİ A., Arias-Moliz M. T.

AUSTRALIAN ENDODONTIC JOURNAL, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2022
  • Doi Number: 10.1111/aej.12660
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Keywords: 2-Hydroxyisocaproic acid, calcium hydroxide, endodontics, mineral trioxide aggregate, root canal medicaments, TRIPLE ANTIBIOTIC PASTE, PASSIVE ULTRASONIC IRRIGATION, INTRACANAL MEDICAMENTS, CALCIUM HYDROXIDE, RESISTANCE, DIAMETER
  • Hacettepe University Affiliated: Yes


This study aimed to evaluate the removal of 2-hydroxyisocaproic acid (HICA) from the root canal system and its effect on the bond strength of the mineral trioxide aggregate (MTA). 126 single-rooted teeth were divided into 3 experimental groups (n = 36) that were treated with double antibiotic paste (DAP), HICA and calcium hydroxide (CH) and one control group (n = 18). In the first part, 18 teeth from each experimental group (n = 54) were examined to remove HICA from the root canal. In the second part, 72 teeth (3 experimental groups (n = 54) and one control group (n = 18)) were used for the evaluation of the push-out bond strength of MTA. There was no statistically significant difference between HICA, DAP and CH residues (p > 0.05). HICA group showed significantly less push-out bond strength (p < 0.05). DAP, HICA and CH could not be removed entirely from the root canal. HICA significantly reduced the bond strength of the MTA.