Possible therapeutic role of vitamin D-3 in aggressive fibromatosis

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Ferah Y., Ayse K., Mustafa C., Ugur S., Murat G., Lale A.

JAPANESE JOURNAL OF CLINICAL ONCOLOGY, vol.34, no.8, pp.472-475, 2004 (SCI-Expanded, Scopus)

• Publication Type: Article / Article
• Volume: 34 Issue: 8
• Publication Date: 2004
• Doi Number: 10.1093/jjco/hyh075
• Journal Name: JAPANESE JOURNAL OF CLINICAL ONCOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.472-475
• Open Archive Collection: AVESIS Open Access Collection
• Hacettepe University Affiliated: No

Abstract

Desmoids, also known as aggressive fibromatoses, are locally invasive tumors that are intermediate in their biological behavior that lies between benign fibrous proliferations and low-grade fibrosarcomas. In this report, we present a case of a young female patient with a huge tumoral mass located in the right shoulder region that recurred after total resection and was resistant to radio-chemo-hormonal therapy. Eventually, she responded to 1,25-(OH)(2)-vitamin D-3 treatment.