EXPERT OPINION ON EMERGING DRUGS, cilt.16, sa.4, ss.647-667, 2011 (SCI-Expanded)
Introduction: The incidence of breast cancer at an advanced stage has decreased in the modern world due to screening programs and usage of novel chemotherapy agents at an adjuvant setting. Recurrence is the major problem seen in > 50% of breast cancer patients diagnosed at an early stage. Developing new drugs for metastatic breast cancer is a huge and challenging research area.