Chlorogenic Acid Containing Bioinspired Polyurethanes: Biodegradable Medical Adhesive Materials


ATEŞ B., KÖYTEPE S., Karaaslan M. G. , Balcioglu S., Gulgen S., DEMİRBİLEK M. , ...More

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, vol.64, no.12, pp.611-619, 2015 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 12
  • Publication Date: 2015
  • Doi Number: 10.1080/00914037.2014.996710
  • Title of Journal : INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
  • Page Numbers: pp.611-619

Abstract

Highly adhesive bioinspired polyurethanes (PUs) based on the chlorogenic acid (CLA) were prepared from 4,4'-methylenebis (cyclohexyl isocyanate) (MCI) and polyethylene glycol 200 (PEG 200). The polyurethanes exhibited the lowest glass transition temperature (T-g), improved thermal stability and good adhesive properties. The highest adhesion strength was found as 373.3 +/- 47.5 kPa for 10% CLA containing PUs. The polyurethanes were observed to be biodegradable and were in the range of 19-24% for 8 weeks as depending on chlorogenic acid containing of PUs. As a result, prepared biocompatible-adhesive bioinspired polyurethanes are good candidates for medical applications as a tissue adhesive material.