Methothrexate attenuates early neutrophil infiltration and the associated lipid peroxidation in the injured spinal cord but does not induce neurotoxicity in the uninjured spinal cord in rats

Sanli A. M., Serbes G., SARGON M. F., ÇALIŞKAN M., Kilinc K., Bulut H., ...More

ACTA NEUROCHIRURGICA, vol.154, no.6, pp.1045-1054, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 154 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1007/s00701-012-1302-8
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1045-1054
  • Hacettepe University Affiliated: Yes


The goal of most acute therapies for spinal cord injury (SCI) in humans include attenuation of the early inflammatory response and may limit the extent of tissue injury and the consequent disability.